Complex I subunit NDUFS4 monoclonal antibody
|
Catalog No. MS104
|
|
|
$325.00 - 100 µg
|
|
This antibody can also be purchased as part of a Sample Pack.
|
UniProt Number:
|
O43181
|
|
Alternate Names:
|
NADH-ubiquinone oxidoreductase 18 kDa subunit, Complex I-18 kDa (Short name=CI-18 kDa), Complex I-AQDQ (Short name=CI-AQDQ)
|
|
Structure and Function:
|
NDUFS4 is an 18-kDa subunit of Complex I, a 45-subunit complex of the respiratory chain. The NDUFS4 subunit makes up part of the iron-sulfur (IP) fragment of the protein. It has been claimed that the NDUFS4 subunit is phosphorylated in a cAMP dependent pathway that controls the activity of complex I. Mutations in this subunit, most often leading to loss of synthesis of the polypeptide, have been related to Complex I dysfunction in a number of patients with early onset mitochondrial diseases. It is thought that the subunit does not contribute to catalytic functions of Complex I. Useful in studies of Complex I assembly and Complex I deficiency in patients.
|
|
|
|
Product Specifications
|
|
|
Applications:
|
Western blotting
|
|
Species Reactivity:
|
human, bovine, mouse, rat
|
|
Host Species:
|
mouse
|
|
Isotype:
|
IgG1, κ
|
|
Clone ID:
|
2C7CD4AG3
|
|
Concentration:
|
1 mg/mL in Hepes-Buffered Saline (HBS)-Buffered Saline (HBS) with 0.02% azide as a preservative.
|
|
Suggested Working Concentration:
|
1 µg/mL for Western blotting
|
|
Storage Conditions:
|
Store at 4°C. Do not freeze.
|
|
Country of Origin:
|
USA
|
Top
|
|
|
|
|
WB Images
(click to enlarge)
Figure 1. Isolated mitochondria from human heart (lane 1), bovine heart (lane 2), rat heart (lane 3), and mouse heart (lane 4), detected with (MS104) anti-NDUFS4 antibody.
|
Top
|
|
|
|
|
Have you published studies using this product?
Let us know by filling out this form and receive a $100 discount on your next order.
Top
|
|
|
|
CART
